![]() What is N,N-Dimethylglycine (DMG)? N,N-Dimethylglycine is a tertiary amino acid, the dimethylated derivative of glycine, and is a natural component of animal and plant metabolism. ![]() It is a derivative of the amino acid glycine and is a natural product of choline metabolism in the body. Although DMG is in popular clinical use, controlled trials to date show little anticonvulsant activity.Äimethylglycine (DMG) is a supplement that is often used as a performance enhancer in racing animals such as dogs and horses for its alleged ability to reduce lactic acid buildup and therefore its ability to reduce muscle fatigue. DMG is a glycine receptor agonist that is thought to have anticonvulsant activity in gamma-aminobutyric acid (GABA) – deficient seizure models.
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